INTRANASAL IMMUNIZATION WITH A BUCL8-BASED VACCINE AMELIORATES BACTERIAL BURDEN AND PATHOLOGICAL INFLAMMATION, AND PROMOTES AN IGG2A/B DOMINANT RESPONSE IN AN OUTBRED MOUSE MODEL OF BURKHOLDERIA INFECTION

Burkholderia pseudomallei is a gram-negative bacterium that is the etiological agent of the tropical disease melioidosis.Currently, there is no licensed vaccine for melioidosis, but numerous candidates are being tested for protective efficacy and characterization of the elicited immune response.Our lab has previously reported the immunogenicity of

The gross anatomy of skateboards the digital flexors tendons and the distal accessory ligament of the Catalan Pyrenean Horse, an equine trait breed from Catalonia (NE Spain), is presented here.Research has been based on the dissection of isolated 10 right forelimbs, 10 left forelimbs, six right hindlimbs and five left hindlimbs (total 31 distal lim

Hypertrophic cardiomyopathy (HCM) is a common heart disease in humans and cats, nonetheless, the disease pathogenesis is still poorly understood.MicroRNAs are suspected to be involved in the disease process but the myocardial microRNA expression pattern in Rolling Machines cats has not been identified.We hypothesized that microRNA profiles differ b

The increasing intensity and frequency of extreme weather events resulting from climate change have Grinders led to grid outages and other negative consequences.To ensure the resilience of buildings which serve as primary shelters for occupants, resilient strategies are being developed to improve their ability to withstand these extreme events (e.g

The concept of Historic Urban Landscape, which now guides the conservation and promotion of numerous heritage sites across the world, is based on the recognition of the complexity of the urban environment, seen as a dynamic system of cultural and natural features.This paper aims at presenting an ongoing reassessment of the meaning of a historic art